James Pirruccello, MD

Post-Doctoral Research Fellow

James is a research fellow interested in advancing our understanding of ischemic heart disease and myocardial infarction, particularly by using genetics and machine learning. He is also interested in translating discoveries into tools that can be used at scale in clinical care.

James was raised in Nevada, completed his BS in Molecular Biophysics and Biochemistry at Yale, received his MD from the Johns Hopkins University School of Medicine in 2013, and finished his internal medicine training at the Massachusetts General Hospital in 2016. He is currently training in cardiology at MGH.

James also worked in the Kathiresan Lab from 2009-2011 as a medical student researcher supported by the Sarnoff Cardiovascular Research Foundation. A key research contribution during this period of training was using exome sequencing to discover null alleles at ANGPTL3 as the cause of familial combined hypolipidemia.  This work was published in the N Engl J Med.